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Check Intently (one)mitotane decreases levels of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Mitotane is often a strong inducer of cytochrome P-4503A4; observe when coadministered with CYP3A4 substrates for feasible dosage adjustments.ceritinib will boost the level or outcome of diazepam by impac